' 
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 4 Reviews
8.6
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Vitamin B12 (as Methylcobalamin)
1,500 mcg
62500%
Top Medical Research Studies
8
Vitamin B12 reduces cardiovascular risks
Association of MTHFR C677T, MTHFRA1298C, and MTRRA66G Gene Polymorphisms with Hyperhomocysteinemia and Its Modulation by the Combined Effect of Vitamin B12 and Folate in Chinese Population with Hypertension.
Moderate relevance to findings
We explored the connection between vitamin B12, genetic factors, and cardiovascular health in a group of Chinese adults suffering from hypertension. By analyzing the genetic variations of individuals, we aimed to understand how these may influence levels of homocysteine, an amino acid that can impact heart health when present in high amounts.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
Read More
7
Vitamin deficiencies affect blood pressure
The impact of folic acid/VB12 deficiency on essential hypertension in children and adolescents: from a nested case-control and a cohort study.
Significant findings on hypertension
We set out to understand how serum folic acid (FA) and vitamin B12 (VB12) levels relate to elevated blood pressure in children and adolescents. Our research included both a nested case-control and a cohort study, focusing on participants from primary schools. We observed that participants with elevated blood pressure had notably lower levels of folic acid and vitamin B12 compared to those with normal blood pressure.
Moreover, these children also had higher levels of homocysteine, a substance that can be harmful in excessive amounts. Among those who were overweight and obese, we found that those with high blood pressure had even lower levels of folic acid. The data suggested a significant connection: higher levels of folic acid were associated with better blood pressure outcomes, and this relationship remained even after accounting for vitamin B12 and homocysteine levels.
Additionally, our cohort study highlighted that both systolic and diastolic blood pressure measurements were lower in children with high folic acid exposure compared to those with low exposure. Overall, our findings indicated that deficiencies in folic acid and vitamin B12 during childhood can contribute to elevated blood pressure, potentially influencing cardiovascular health. Therefore, it's important to ensure adequate intake of these vitamins, either through diet or supplementation.
Moreover, these children also had higher levels of homocysteine, a substance that can be harmful in excessive amounts. Among those who were overweight and obese, we found that those with high blood pressure had even lower levels of folic acid. The data suggested a significant connection: higher levels of folic acid were associated with better blood pressure outcomes, and this relationship remained even after accounting for vitamin B12 and homocysteine levels.
Additionally, our cohort study highlighted that both systolic and diastolic blood pressure measurements were lower in children with high folic acid exposure compared to those with low exposure. Overall, our findings indicated that deficiencies in folic acid and vitamin B12 during childhood can contribute to elevated blood pressure, potentially influencing cardiovascular health. Therefore, it's important to ensure adequate intake of these vitamins, either through diet or supplementation.
Read More
Most Useful Reviews
9.5
Improved red blood cells
This form of B12 genuinely works, as our lab results confirmed. While dealing with pernicious anaemia linked to blood cancer, I found traditional B12 ineffective. Once we began using this activated version, we observed a halt in the decline of hemoglobin levels, eventually seeing improvement. Regular use kept my red blood cell count above 8.5. It's vital for the formation of red blood cells, and many doctors underestimate its importance, despite the need for sufficient iron.
Read More
8.8
Beneficial for recovery
I have found this product beneficial as it positively impacts cardiovascular disease, cognitive ability, and recovery from fatigue.
Read More
7.5
Gradual pain relief
After getting shingles, I struggled with pain despite medical treatment. Knowing B12 could help, I opted for this well-reviewed product. Initially sceptical, I took one tablet nightly. Although the effect wasn't immediate, over two weeks, my pain gradually lessened and eventually vanished. I now take it twice a week.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
Vitamin B12 reduces cardiovascular risks
Association of MTHFR C677T, MTHFRA1298C, and MTRRA66G Gene Polymorphisms with Hyperhomocysteinemia and Its Modulation by the Combined Effect of Vitamin B12 and Folate in Chinese Population with Hypertension.
Moderate relevance to findings
We explored the connection between vitamin B12, genetic factors, and cardiovascular health in a group of Chinese adults suffering from hypertension. By analyzing the genetic variations of individuals, we aimed to understand how these may influence levels of homocysteine, an amino acid that can impact heart health when present in high amounts.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
Read More
7
Vitamin deficiencies affect blood pressure
The impact of folic acid/VB12 deficiency on essential hypertension in children and adolescents: from a nested case-control and a cohort study.
Significant findings on hypertension
We set out to understand how serum folic acid (FA) and vitamin B12 (VB12) levels relate to elevated blood pressure in children and adolescents. Our research included both a nested case-control and a cohort study, focusing on participants from primary schools. We observed that participants with elevated blood pressure had notably lower levels of folic acid and vitamin B12 compared to those with normal blood pressure.
Moreover, these children also had higher levels of homocysteine, a substance that can be harmful in excessive amounts. Among those who were overweight and obese, we found that those with high blood pressure had even lower levels of folic acid. The data suggested a significant connection: higher levels of folic acid were associated with better blood pressure outcomes, and this relationship remained even after accounting for vitamin B12 and homocysteine levels.
Additionally, our cohort study highlighted that both systolic and diastolic blood pressure measurements were lower in children with high folic acid exposure compared to those with low exposure. Overall, our findings indicated that deficiencies in folic acid and vitamin B12 during childhood can contribute to elevated blood pressure, potentially influencing cardiovascular health. Therefore, it's important to ensure adequate intake of these vitamins, either through diet or supplementation.
Moreover, these children also had higher levels of homocysteine, a substance that can be harmful in excessive amounts. Among those who were overweight and obese, we found that those with high blood pressure had even lower levels of folic acid. The data suggested a significant connection: higher levels of folic acid were associated with better blood pressure outcomes, and this relationship remained even after accounting for vitamin B12 and homocysteine levels.
Additionally, our cohort study highlighted that both systolic and diastolic blood pressure measurements were lower in children with high folic acid exposure compared to those with low exposure. Overall, our findings indicated that deficiencies in folic acid and vitamin B12 during childhood can contribute to elevated blood pressure, potentially influencing cardiovascular health. Therefore, it's important to ensure adequate intake of these vitamins, either through diet or supplementation.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Improved red blood cells
This form of B12 genuinely works, as our lab results confirmed. While dealing with pernicious anaemia linked to blood cancer, I found traditional B12 ineffective. Once we began using this activated version, we observed a halt in the decline of hemoglobin levels, eventually seeing improvement. Regular use kept my red blood cell count above 8.5. It's vital for the formation of red blood cells, and many doctors underestimate its importance, despite the need for sufficient iron.
Read More
8.8
Beneficial for recovery
I have found this product beneficial as it positively impacts cardiovascular disease, cognitive ability, and recovery from fatigue.
7.5
Gradual pain relief
After getting shingles, I struggled with pain despite medical treatment. Knowing B12 could help, I opted for this well-reviewed product. Initially sceptical, I took one tablet nightly. Although the effect wasn't immediate, over two weeks, my pain gradually lessened and eventually vanished. I now take it twice a week.
Read More
8.8
Essential for health
Vitamin B12 is crucial for optimising brain, nerve, and blood health. Deficiencies in this nutrient are alarming, as it reduces fatigue, enhances memory, and promotes the production of red blood cells, crucial in combating cardiovascular disease. For optimal health, it's essential to take B12 regularly.
Read More
